Difference between revisions of "DZI19-121-Case-1"

From MGH Learn Pathology
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{{ServiceRequestCase
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|order_date=September 11, 2019 01:57:23 PM
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|identifier=DZI19-121-Case-1
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|user=Em99
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|intent=order
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|slide_stain=H&E
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|category=409073007
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|basedOn=DZI19-121
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|qctime=Sep 13, 2019 20:41:00
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|supportingInfo=Integrated diagnosis: GLIOBLASTOMA, IDH-WILDTYPE
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|order_date=September 11, 2019 01:57:23 PM
 
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|user=Em99
 
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|dziorder=DZI19-121
 
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|case_id=1
 
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|publish_timestamp=2019/09/13 19:00
 
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|clinical_hx=63 year old woman with a history of breast CA s/p bilateral mastectomy presents with difficulty walking, staggering gait, and fatigue
 
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|case_diagnosis=Integrated diagnosis: GLIOBLASTOMA, IDH-WILDTYPE
 
  
 
Histological diagnosis: Glioblastoma
 
Histological diagnosis: Glioblastoma
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IHC for mutant ID1(R132H) was negative and is sufficient in patients >55 years of age to determine IDH status (rare to find non-canonical mutations in this group).
 
IHC for mutant ID1(R132H) was negative and is sufficient in patients >55 years of age to determine IDH status (rare to find non-canonical mutations in this group).
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|gross=[[File:Case 1.png|thumb|MRI: T1 coronal post gadolinium shows a large mass with irregular peripheral contrast enhancement]]
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|reasonCode=63 year old woman with a history of breast CA s/p bilateral mastectomy presents with difficulty walking, staggering gait, and fatigue
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|authoredOn=September 11, 2019 01:57:23 PM
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|order_date=September 13, 2019 05:44:47 PM
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|authoredOn=September 11, 2019 01:57:23 PM
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|media_text=MRI: T1 coronal post gadolinium shows a large mass with irregular peripheral contrast enhancement
 
 
}}
 
}}

Latest revision as of 13:23, December 9, 2024

DZI19-121-Case-1
63 year old woman with a history of breast CA s/p bilateral mastectomy presents with difficulty walking, staggering gait, and fatigue
Integrated diagnosis: GLIOBLASTOMA, IDH-WILDTYPE

Histological diagnosis: Glioblastoma

WHO histological grade: IV

Molecular information: IDH1: negative (R132H immunohistochemistry) MGMT promoter: methylated (methylation specific PCR)

IHC for mutant ID1(R132H) was negative and is sufficient in patients >55 years of age to determine IDH status (rare to find non-canonical mutations in this group).
December 31, 1969 7:00:00 PM






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