Difference between revisions of "DZI19-121-Case-1"

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{{dziSlide
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{{ServiceRequestCase
|order_date=September 11, 2019 01:57:23 PM
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|identifier=DZI19-121-Case-1
|user=Em99
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|intent=order
|slide_stain=H&E
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|category=409073007
|slide_anatomy=Show
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|priority=routine
 +
|orderDetail=case
 +
|locationCode=learn
 +
|basedOn=DZI19-121
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|code=faculty
 +
|supportingInfo=Integrated diagnosis: GLIOBLASTOMA, IDH-WILDTYPE
 +
 
 +
Histological diagnosis: Glioblastoma
 +
 
 +
WHO histological grade: IV
 +
 
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Molecular information:
 +
IDH1: negative (R132H immunohistochemistry)
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MGMT promoter: methylated (methylation specific PCR)
 +
 
 +
IHC for mutant ID1(R132H) was negative and is sufficient in patients >55 years of age to determine IDH status (rare to find non-canonical mutations in this group).
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|reasonCode=63 year old woman with a history of breast CA s/p bilateral mastectomy presents with difficulty walking, staggering gait, and fatigue
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|subject=MGH
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|performer=MML55
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|authoredOn=September 11, 2019 01:57:23 PM
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|requester=Em99
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|sequence=1
 +
|access=public
 
}}
 
}}
{{dziCase
+
{{Media
|order_date=September 11, 2019 01:57:23 PM
+
|basedOn=DZI19-121-Case-1
|user=Em99
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|type=image
|dziorder=DZI19-121
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|view=show
|case_id=1
+
|partOf=DZI19-121
|clinical_hx=63 year old woman with a history of breast CA s/p bilateral mastectomy presents with difficulty walking, staggering gait, and fatigue
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|frames=1
|gross=[[File:Case 1.png|thumb|MRI: T1 coronal post gadolinium shows a large mass with irregular peripheral contrast enhancement]]
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|reasonCode=H&E
 +
|identifier=DZI19-121-Case-1_1
 +
|createdDateTime=September 11, 2019 01:57:23 PM
 +
|operator=Em99
 +
|modality=ndpi
 
}}
 
}}
{{dziMedia
+
{{status
|order_date=September 13, 2019 05:44:47 PM
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|status=active
|user=Em99
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|requester=Em99
|media_filename=Case_1.png
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|authoredOn=September 11, 2019 01:57:23 PM
|media_text=MRI: T1 coronal post gadolinium shows a large mass with irregular peripheral contrast enhancement
 
 
}}
 
}}

Latest revision as of 13:23, December 9, 2024

DZI19-121-Case-1
63 year old woman with a history of breast CA s/p bilateral mastectomy presents with difficulty walking, staggering gait, and fatigue
Integrated diagnosis: GLIOBLASTOMA, IDH-WILDTYPE

Histological diagnosis: Glioblastoma

WHO histological grade: IV

Molecular information: IDH1: negative (R132H immunohistochemistry) MGMT promoter: methylated (methylation specific PCR)

IHC for mutant ID1(R132H) was negative and is sufficient in patients >55 years of age to determine IDH status (rare to find non-canonical mutations in this group).
December 31, 1969 7:00:00 PM