Difference between revisions of "DZI19-121-Case-4"

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|identifier=DZI19-121-Case-4
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|category=409073007
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|basedOn=DZI19-121
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|supportingInfo=Integrated diagnosis:
 +
DIFFUSE ASTROCYTIC GLIOMA, IDH-WILDTYPE, WITH MOLECULAR FEATURES OF GLIOBLASTOMA
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Histological diagnosis: Anaplastic astrocytoma
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WHO (integrated histological and molecular grade): IV
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Molecular information:
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IDH: wildtype (IDH1/2 PCR sequencing)
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P53: positive in most tumor cells (immunohistochemistry, consistent with mutation)
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ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype)
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MGMT promoter: unmethylated (methylation specific PCR)
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EGFR amplification: PRESENT (FISH)
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|reasonCode=67 year old man with new onset of seizures
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|subject=MGH
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|performer=MML55
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|authoredOn=September 11, 2019 01:57:55 PM
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|requester=Em99
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|sequence=4
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|access=public
 
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|authoredOn=September 11, 2019 01:57:55 PM
 
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Latest revision as of 13:23, December 9, 2024

DZI19-121-Case-4
67 year old man with new onset of seizures
Integrated diagnosis:

DIFFUSE ASTROCYTIC GLIOMA, IDH-WILDTYPE, WITH MOLECULAR FEATURES OF GLIOBLASTOMA

Histological diagnosis: Anaplastic astrocytoma

WHO (integrated histological and molecular grade): IV

Molecular information: IDH: wildtype (IDH1/2 PCR sequencing) P53: positive in most tumor cells (immunohistochemistry, consistent with mutation) ATRX: nuclear expression retained (immunohistochemistry, consistent with wildtype) MGMT promoter: unmethylated (methylation specific PCR)

EGFR amplification: PRESENT (FISH)
December 31, 1969 7:00:00 PM