Difference between revisions of "WSI24-127"

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|subject=MGH
 
|subject=MGH
 
|performer=MM768
 
|performer=MM768
|occurrenceDateTime=2024/06/22 12:00:00-07:00
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|occurrenceDateTime=2025/06/22 12:00:00-07:00
 
|supportingInfo=Pulmonary Pathology
 
|supportingInfo=Pulmonary Pathology
|requisition=Mystery Case
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|requisition=Mystery Case 2024
|reasonCode=Topic
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|reasonCode=Mystery Case
 
|identifier=WSI24-127
 
|identifier=WSI24-127
 
|status=active
 
|status=active

Latest revision as of 12:36, June 12, 2024


Request type Study
Subspecialty Pulmonary Pathology
Set Mystery Case 2024
Topic Mystery Case
Presenter Mino-Kenudson, Mari,MD
Date and time Sunday, June 22, 2025 3:00 PM


Toggle columns: Diagnosis

Case Clinical history Requester Diagnosis
Case Clinical history Requester Diagnosis

Case 1


A 70-year-old woman with a lung nodule in the left lower lobe. Kx601 Secretory carcinoma

Case 2


A 65-year old man with persistent fever dyspnea persistent cough and hemolysis was referred to the multidisciplinary board for interstitial lung diseases. Previous transbronchial biopsies and radiology at a referring center rendered a tentative diagnosis of hypersensitivity pneumonitis. However based on the unusual clinical course with persistent fever of unknown origin (> 2 months) and low lymphocyte count on BAL a VATS thoracic biopsy was performed. Kx601 Intravascular large B-cell lymphoma involving the lung

Case 3


A 40-year-old male never-smoker presented with a 1 year history of progressive dyspnea on exertion and dry cough for six months occasional wheezing and chronic fatigue. The patient is an engineer working as project manager but reported a history of exposure to engine exhaust benzene and carbon black in the 90’s. His medical history included ocular migraines and intermittent “hives with stress”. Pulmonary function tests showed an FEV1/FVC of 48% FEV1 29% and DLCO 44%. Alpha-1 antitrypsin levels were found normal several times. ANA and RF were negative. IgG levels were low 595. Kx601 Panacinar emphysema with small vessel vasculitis. Hypocomplementemic urticarial vasculitis syndrome

Case 4


A woman in her 60s with history of heavy smoking (> 40 pack/years) presented with a slowly growing right lower lobe nodule that was found by a low-dose CT screening program. Kx601 Clear cell stromal tumor of the lung with YAP1::TFE3 fusion

Case 5


A 52-year-old female never smoker was incidentally found to have a 10mm well-circumscribed nodule in the superior segment of the left lung lower lobe by CT scan. The lesion was not amenable to biopsy and the patient underwent a surgical wedge resection. Kx601 Pulmonary Benign Notochordal cell tumour