| _creationDate | March 20, 2025 |
| _modificationDate | March 20, 2025 |
| _creator | Si787 |
| _fullText | {{ServiceRequestCase
|identifier=WSI21-134-Case-38
|intent=order
|code=study
|category=409073007
|subject=MGH
|requester=Ndk6
|performer=MGH
|orderDetail=case
|locationCode=learn
|access=Public
|status=completed
|origin=CPOE
|priority=routine
|basedOn=WSI21-134
|requisition=Cytology
|reasonCode=58 y ... |
| _numRevisions | 1 |
| _isRedirect | No |
| identifier | WSI21-134-Case-38 |
| basedOn | WSI21-134 |
| requisition | Cytology |
| intent | order |
| category | 409073007 |
| priority | routine |
| code | study |
| orderDetail | case |
| subject | MGH |
| occurrenceDateTime | December 31, 1969 7:00:00 AM |
| authoredOn | March 20, 2025 3:32:04 PM |
| requester | Ndk6 |
| performer | MGH |
| locationCode | learn |
| reasonCode | 58 yo M post renal transplant with pericardial effusion |
| supportingInfo | Suspicious for malignancy- Single cells with prominent nucleoli and coarse chromatin highly suspicious for
malignant lymphoma • large cell type.
PERICARDIAL FLUID CELLBLOCK:
Primary effusion lymphoma (HHV8+) consistent with a post transplantation lymphoproliferative disorder (see note).
Note: Immunostains on the cell block show many large atypical lymphoid cells that are positive for CD30 • MUM1 and HHV8. The large cells are negative for CD19 • CD3 • CD5 • CD10 • BCL6 • BCL2 and CD21. Rare enlarged cells are CD20+ but overall large cells are negative for CD20. CD3 and CD5 stain many admixed small T cells. MYC stains less than 10% of all cells • mostly weakly. Most large cells (approximately 90%) are positive for Ki-67 (proliferation). In situ hybridization for EBER is negative.
In summary • the findings are those of a primary effusion lymphoma • which is a rare • HHV8-related large B-cell lymphoma. In this patient status post renal transplant • the lymphoma can be considered an unusual type of post transplantation lymphoproliferative disorder. |
| sequence | 38 |
| access | Public |
| status | completed |
| identifier | WSI21-134-Case-38 |
| requester | Ndk6 |
| authoredOn | March 20, 2025 3:32:04 PM |
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| status | completed |
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| modality | mrxs |
| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | LB |
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| createdDateTime | March 20, 2025 3:32:04 PM |
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| reasonCode | H&E |
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| note | null |
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| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
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| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | CD20 (T-C) B1 |
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| note | null |
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| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | CD19 (T-C) B6 |
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| note | null |
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| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | CD3 (T-C) B1 |
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| note | null |
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| identifier | d70cd81c-14d4-42fa-9a73-c486af307fa1 |
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| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | CD5 (T-C) B6 |
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| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | CD10 (T-C) B6 |
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| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | BCL6 (T-C) B2 |
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| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | qBCL2 |
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| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | CD30 (QUANT) B6 |
| bodySite | null |
| frames | 11 |
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| note | null |
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| status | completed |
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| modality | mrxs |
| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | CMYC (QUANT) |
| bodySite | null |
| frames | 12 |
| content | 6b92eab8-7db6-4471-8721-09a588c07041.mrxs |
| note | null |
| subject | null |
| identifier | ca779089-9f80-4951-bf61-7dfe7209b66f |
| basedOn | WSI21-134-Case-38 |
| partOf | WSI21-134 |
| status | completed |
| type | null |
| modality | mrxs |
| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | MUM-1 (T-C) B3 |
| bodySite | null |
| frames | 13 |
| content | ca779089-9f80-4951-bf61-7dfe7209b66f.mrxs |
| note | null |
| subject | null |
| identifier | 2991dde2-1fa5-436b-b3f1-2eaab68b78e1 |
| basedOn | WSI21-134-Case-38 |
| partOf | WSI21-134 |
| status | completed |
| type | null |
| modality | mrxs |
| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | Ki67 (T-C) B4 |
| bodySite | null |
| frames | 14 |
| content | 2991dde2-1fa5-436b-b3f1-2eaab68b78e1.mrxs |
| note | null |
| subject | null |
| identifier | 6e0d1916-433b-442b-9c69-40f658453e68 |
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| status | completed |
| type | null |
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| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | CD21 (T-C) B6 |
| bodySite | null |
| frames | 15 |
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| note | null |
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| status | completed |
| type | null |
| modality | mrxs |
| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | EBER B2 |
| bodySite | null |
| frames | 16 |
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| note | null |
| subject | null |
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| status | completed |
| type | null |
| modality | mrxs |
| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | EBER RNA Control B2 |
| bodySite | null |
| frames | 17 |
| content | bfcc4d08-cd15-4aea-aa62-cc170945dd11.mrxs |
| note | null |
| subject | null |
| identifier | 1997170f-4503-4d83-b839-7d7f5fa492e4 |
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| status | completed |
| type | null |
| modality | mrxs |
| view | hide |
| createdDateTime | March 20, 2025 3:32:04 PM |
| operator | Ndk6 |
| reasonCode | HHV-8 B3 |
| bodySite | null |
| frames | 18 |
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| note | null |
| subject | null |