_creationDate | October 21, 2020 |
_modificationDate | December 9, 2024 |
_creator | Vn048 |
_fullText | {{ServiceRequestCase
|identifier=DZI20-210-Case-20
|intent=order
|category=409073007
|priority=routine
|orderDetail=case
|locationCode=learn
|basedOn=DZI20-210
|code=faculty
|supportingInfo=SKIN, LEFT UPPER DORSAL ARM, PUNCH BIOPSY: Cutaneous T cell lymphoma with gamma/delta phenotype.
IHC: atypica ... |
_numRevisions | 5 |
_isRedirect | No |
identifier | DZI20-210-Case-20 |
basedOn | DZI20-210 |
requisition | null |
intent | order |
category | 409073007 |
priority | routine |
code | faculty |
orderDetail | case |
subject | MGH |
occurrenceDateTime | December 31, 1969 7:00:00 PM |
authoredOn | October 21, 2020 3:13:43 PM |
requester | Vn048 |
performer | VN048 |
locationCode | learn |
reasonCode | Persistent scaly plaques involving bilateral arms over 30 years |
supportingInfo | SKIN • LEFT UPPER DORSAL ARM • PUNCH BIOPSY: Cutaneous T cell lymphoma with gamma/delta phenotype.
IHC: atypical cells are of T-cell lineage (CD3+) with gamma delta T-cell receptor phenotype • largely lack CD4 and CD8 expression • and demonstrate reduced expression of CD2 and CD7. CD56 is negative • and of the cytotoxic markers • only perforin shows weak positivity. The dermal infiltrate appears to be reactive with positivity for BetaF1 • subset positivity for CD4 and CD8 • and relatively strong expression of PD1 • ICOS • PD-L1 • and CD25. Adnexotropism or large cell transformation are not seen. Subcutaneous fat is not involved. T-cell receptor gene rearrangement studies demonstrate clonal rearrangement of beta chain. DDX: incipient/evolving cutaneous gamma-delta T-cell lymphoma and mycosis fungoides with gamma-delta phenotype. |
specimen | null |
bodySite | null |
sequence | 20 |
access | public |
identifier | DZI20-210-Case-20_1 |
basedOn | DZI20-210-Case-20 |
partOf | DZI20-210 |
status | completed |
type | image |
modality | mrxs |
view | show |
createdDateTime | October 21, 2020 3:13:43 PM |
operator | Vn048 |
reasonCode | H&E |
bodySite | null |
frames | 1 |
content | DZI20-210-Case-20_1.mrxs |
note | null |
subject | Z0FBQUFBQmZrRkF2T0lCLUJUX1pYUVNPMXlfYk9aUDVSbWtUR09ITjl0dTQybWdaS2FKUjZLVlRxc1JZVTl3YUZrRnExZzN5MGNSZS1IaVhreC1lU1pfM3BqdzY1TU5QUnc9PQ |
status | active |
identifier | DZI20-210-Case-20 |
requester | Vn048 |
authoredOn | October 21, 2020 3:13:43 PM |