WSI23-41-Case-1

Sequence	Case	Clinical history	Diagnosis
1	WSI23-41-Case-1 WSI23-41-Case-1	84 year old male with bladder outlet obstruction, TURP 84 year old male with bladder outlet obstruction, TURP	High grade prosttic adenocrcinoma, gleason score 5 of 5 with neuroendocrine differentiation High grade prosttic adenocrcinoma, gleason score 5 of 5 with neuroendocrine differentiation
2	WSI23-41-Case-2 WSI23-41-Case-2	71 year old male with history of prostate cancer s/p prostatectomy and radiation in 2010, now with S2 spinal lesion 71 year old male with history of prostate cancer s/p prostatectomy and radiation in 2010, now with S2 spinal lesion	Metastatic prostatic adenocarcinoma Metastatic prostatic adenocarcinoma
3	WSI23-41-Case-3 WSI23-41-Case-3	61 year old with prostate cancer 61 year old with prostate cancer	Adenocarcinoma, gleason score 3+3=6/10, bilateral perineural invasion, neg margins, neg SV and vas def Adenocarcinoma, gleason score 3+3=6/10, bilateral perineural invasion, neg margins, neg SV and vas def
4	WSI23-41-Case-4 WSI23-41-Case-4	86 year old male with hard nodular prostate and PSA 175 86 year old male with hard nodular prostate and PSA 175	Prostatic adenocarcinoma, gleason score 5+4=9/10, involving >90% each of 2/2 cores. + PNI tumor invades skeletal muscle and adipose tissue. Sheet-like growth & foamy cell and signet ring-like changes Prostatic adenocarcinoma, gleason score 5+4=9/10, involving >90% each of 2/2 cores. + PNI tumor invades skeletal muscle and adipose tissue. Sheet-like growth & foamy cell and signet ring-like changes
5	WSI23-41-Case-5 WSI23-41-Case-5	62 year old man with radical prostatectomy revealing 3+3=6/10 cancer. Here is a separate finding. 62 year old man with radical prostatectomy revealing 3+3=6/10 cancer. Here is a separate finding.	Senile amyloid of bilateral seminal vesicles Senile amyloid of bilateral seminal vesicles
6	WSI23-41-Case-6 WSI23-41-Case-6	58 year old male with elevated PSA. 58 year old male with elevated PSA.	Prostatic adenocarcinoma 3+4=7/10 with mucinous differentiation +PNI Prostatic adenocarcinoma 3+4=7/10 with mucinous differentiation +PNI
7	WSI23-41-Case-7 WSI23-41-Case-7	65 year old male with ↑ PSA with negative biopsy in 2011, now for TURP 2° to urinary retention symptoms PSA in 2011, 5 ng/mL; post biopsy 10 ng/ml 65 year old male with ↑ PSA with negative biopsy in 2011, now for TURP 2° to urinary retention symptoms PSA in 2011, 5 ng/mL; post biopsy 10 ng/ml	Prostatic adenocarcinoma, gleason score 4+5=9/10 with perineural invasion, infiltrating skeletal muscle Prostatic adenocarcinoma, gleason score 4+5=9/10 with perineural invasion, infiltrating skeletal muscle
8	WSI23-41-Case-8 WSI23-41-Case-8	60 year old male with prostate cancer 60 year old male with prostate cancer	A. Grade 5 prostate carcinoma with PNI in bladder neck. B. 5+4 with EPE, PN1, LVI A. Grade 5 prostate carcinoma with PNI in bladder neck. B. 5+4 with EPE, PN1, LVI
9	WSI23-41-Case-9 WSI23-41-Case-9	80 year old male with history of BPH s/p TURP 2008; 2009 with palp nodule on right lateral prostate 80 year old male with history of BPH s/p TURP 2008; 2009 with palp nodule on right lateral prostate	Prostate adenocarcinoma 4+4 with focal ductal-type features Prostate adenocarcinoma 4+4 with focal ductal-type features
10	WSI23-41-Case-10 WSI23-41-Case-10	57 year old man with urinary outlet obstruction and mildly elevated PSA, 4.88 (11/08) over prior 3.69 (5/08) 57 year old man with urinary outlet obstruction and mildly elevated PSA, 4.88 (11/08) over prior 3.69 (5/08)	Adenocarcinoma, ductal type, gleason score 4+4=8/10. Adenocarcinoma, ductal type, gleason score 4+4=8/10.

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