WSI22-141: Sinonasal and Nasopharynx
From MGH Learn Pathology
Request details
- Request type Study
- Subspecialty Head and Neck
- Set ENT Pathology
- Topic Sinonasal and Nasopharynx
- Presenter Sadow, Peter M.,MD, PhD
- Date and time Saturday, October 1, 2022 12:00 PM
Toggle columns: Diagnosis
| Case | Clinical history | Requester | Diagnosis |
|---|---|---|---|
| Case | Clinical history | Requester | Diagnosis |
|
| 30 year old with multiple years of recurrent sinus infections and asymmetric breathing | Si787 | Chronic rhinosinusitis |
|
| 61 year old male with chronic sinusitis • nasal obstruction • and left maxillary inverted papilloma; here • left sinus contents | Si787 | Schneiderian papilloma • inverted type • extensive. There is no evidence of dysplasia |
|
| 75 year old male with left nasal tumor | Si787 | Sinonasal glomangiopericytoma (1.3 cm) +SMA • + nuclear B catenin • - kerative • - CD34 • -S100 |
|
| 42 year old male with left nasal polyp. Rule out lymphoma | Si787 | c/w aneurysmal bone cyst |
|
| 50 year old female with chronic sinusitis | Si787 | Chronic rhinosinusitis with central nervous tissue |
|
| 66 year old male with h/of nasal polyp | Si787 | Respiratory epithelial adenomatoid hamartoma |
|
| 60 year old male with nasal polyps • sinusitis and left septal lesion | Si787 | Respiratory epithelial adenomatoid hamartoma |
|
| 74 year old female with history of multiple lesions of this type and now with left nasal septum mass | Si787 | Xanthogranuloma (0.7 cm) +CD163 • + CD68 • - ALK-1 • CD1 • CD23 • CD35 |
|
| 15 year old male with nasopharyngeal mass | Si787 | Juvenile nasopharyngeal angiofibroma (4.0 cm) |
|
| 62 year old female with vague history of fibrous dysplasia (not documented at MGH) with prior left sinus biopsy showing polypoid chronic rhinosinusitis. She now has had new onset ofleft supraorbital pain and pressue for 1.5 months. | Si787 | Meningioma • infiltrating sinus tissue and bone |
|
| 36 year old male with right sinonasal mass with worsening nasal obstructive symptom with a one time episode of severe nose bleed almost one year prior. CT shows a 3.4 cm mass centered along the sphenopalatine foramen | Si787 | Juvenile nasopharyngeal angiofibroma |
|
| 59 year old male • endosinus drainage of abscess; orbital abscess | Si787 | Schneiderian papilloma • inverted type. |
|
| 39 year old male with 3 mm lesion superior aspect of inferior turbinate | Si787 | Low grade glandular neoplasm most consistent with an atypical pleomorphic adenoma • sinonasal type |
|
| 72 year old male with intranasal mass • previously biopsied outside • with unusual features. Thought to be benign. | Si787 | Salivary-type carcinoma • low to intermediate grade • with divergent differentiation • arising in association with a hamartoma. |
|
| 40 year old male ith trans-septal nasal mass | Si787 | Glomangiopericytoma with surface ulceration and contact ulcer/pyogenic granuloma |
|
| 49 year old male with a slow-growing • large mass within the maxillary sinus extending to the temporal area as well as the masseter muscles and posteriorly into the cavernous sinus | Si787 | Low grade osteosarcoma |
|
| 20 year old male with sudden onset of anosmia and dysgensia | Si787 | Olfactory neuroblastoma (subtype is esthesioneuroepithelioma) |
|
| 20 year old male with sudden onset of anosmia and dysgensia | Si787 | Olfactory neuroblastoma (subtype is esthesioneuroepithelioma) |
|
| 47 year old female with obstructive nasal mass. Sent with R/O lymhoma | Si787 | Nasopharnygeal carcinoma |
|
| 70 year old male with epistaxis and recurrent left-sided nasal lesion first biopsied 3 years prior | Si787 | Schneiderian papilloma • oncocytic type |
|
| 48 year old male with diplopia and right proptosis. CT - large • enhancing mass emanating from superior right nasal region and ethmoid air cells up to 4.2 cm | Si787 | Sinonasal undifferentiated carcinoma • infiltrating bone • with LVI |
|
| 53 year old male with h/o recurrent respiratory infectious and sinusitis | Si787 | A. Schneiderian papilloma • inverted type with melanosis. B. Melanosis |
|
| 48 year old male with recurring intranasal lesion | Si787 | Schneiderian papilloma • exophytic type (HPV-related) |
|
| 53 year old male with h/o of renal cell carcinoma (clear cell type • grade 3/4) 3 yrs prior who prsents with a lesion of the paranasal sinuses | Si787 | Metastatic clear cell renal cell carcinoma to sinus mucosa |
|
| 47 year old male with congestion of nasal passages and sinuses | Si787 | Chronic rhinosinusitis with numerous non-caseating granulomas c/w sarcoidosis. GMS & PAS/D are negative |
|
| 30 year old male with right maxillary sinus problem presenting with loosening of teeth in right upper maxilla over he course of one year | Si787 | Inflammatory fibroblastic sarcoma • low grade (1 of 3) • 4.0 cm. MITS 11:10 hpf • - ALK-1 • SMA +focal keratin |
|
| 46 year old female with septal deviation and chronic rhinosinusitis | Si787 | Nasal mucosal hamartoma with apocrine and papillary change (0.2 cm) in setting of chronic rhinosinusitis |
|
| 55 year old female with chronic sinusitis | Si787 | Schneiderian papilloma • oncocytic type |
|
| 15 year old female with recurring rhinosinusitis | Si787 | Allergic fungal rhinosinusitis with eosinophils and allergic mucin |
|
| 72 year old female with nasal cavity mass • biopsy | Si787 | High grade carcinoma • NOS |
|
| 21 day old male with nasal congestion and intranasal mass | Si787 | Nasal glial heterotopia (nasal glioma) |
|
| 59 year old female with chronic rhinosinusitis and large antral choanal polyp on the left. | Si787 | Polypoid sinonasal mucinous hamartoma |
|
| 86 year old with left intranasal lesion | Si787 | Basal cell adenoma • tubulotrabecular type (aggregating to 5.0 cm) |
|
| 55 year old male ith 2 year h/o epiphora with imaging revealing a lacrimal sac tumor with boy erosion and invading into the left orbit • nasal cavity and maxillary sinus | Si787 | Adenoid cystic carcinoma • solid and cribriform types |
|
| 65 year old male presents with opacification of right sinus | Si787 | Sinonasal adenocarcinoma • low grade • NOS • with features of intestinal-type • nondiagnostic of |
|
| 53 year old female with left nasal lesion | Si787 | Oncocytoma with cystic and papillary change (0.7 cm) |
|
| 48 year old male with recurrent lesion of the nasal septum | Si787 | Myoepithelial-rich low grade salivary gland neoplasm. 1. Recurrent. 2. Pleomorphic adenoma with elevated risk of recurrence/aggressive behavior as no gross evidence of disease |
|
| 29 year old male with h/o multiorgan failure with nasal necrosis | Si787 | Infiltrative fungal hyphae c/w aspergillus species |
|
| 60 year old female with chronic rhinosinusitis with ethmoid opacification | Si787 | Aspergilloma with polarizable calcium oxalate crystals |
|
| 33 year old female with sinonasal lesion | Si787 | Sinonasal small cell carcinoma |
|
| 34 year old female with nasal mass | Si787 | Osteoblastoma |
|
| 62 year old physician with left nasal mass | Si787 | Low grade • benign-appearing fascicular spindle cell neoplasm suggestive of myepithelial. Focal p63 • focal S100 • - keratins • - SMA |
|
| 88 year old female with lesion in right ala ofnose | Si787 | Sebaceous cell carcinoma (1.7 cm) + PN1 |
|
| 50 year old male with h/o sinonasal tumor | Si787 | Invasive Schneiderian carcinoma with carcinoma in situ |
|
| 64 year old female with h/o sinusitis; now with bony mass • ? fibro-osseous lesion | Si787 | Sinonasal hamartoma |
|
| 54 year old Moroccan male with several years history of intermittent nose bleeds with 4 cm mass in nasopharynx of CT left nasal blockage X 3 months | Si787 | Nasopharyngeal carcinoma • non-keratinizing undifferentiated type. EBER + |
|
| 73 year old male skin of nose | Si787 | Rhinophyoma |
|
| 50 year old male with a nasopharyngeal mass | Si787 | Nasopharyngeal carcinoma • non-keratinizing undifferentiated type. EBER + |
|
| 40 year old male presents with increasing chronic left nasal and sinus congestion with increasing hx of nose bleeds and headache | Si787 | Sinonasal undifferentiated carcinoma • HPV16+ |
|
| 10 year old male with nasal mass | Si787 | Dermoid cyst |
|
| 49 year old female with bilateral skull-based tumor and cranial nerve palsy | Si787 | Adenoid cystic carcinoma • solid and cribriform types + PN1 |
|
| 23 year old male | Si787 | Sinonasal low grade adenocarcinoma • non-intestinal type |
|
| 9 year old male with nasopharyngeal tumor | Si787 | Nasopharyngeal carcinoma • non-keratinizing • undifferentiated type |
|
| 33 year old female | Si787 | Consistent with ecthyma gangrenosum dur to Pseudomonas aeruginosa (Gram negative rods on Brown-Hopps) |
|
| 71 year old female | Si787 | Poorly differentiated neuroendocrine carcinoma |
|
| 63 year old female | Si787 | Schneiderian papilloma • oncocytic type |
|
| 82 year old female | Si787 | Atpical pleomorphic adenoma (5.7 cm) |
|
| 46 year old male | Si787 | Plurihormonal pituitary adenoma • infiltrating sinus mucosa |
|
| 40 year old male | Si787 | Spindle cell squamous cell carcinoma |
|
| 29 year old woman with a history of unilateral conductive hearing loss and unspecified contralateral hearing loss • also with a history of rhinitis • chronic eustachian tube dysfunction and a nasopharyngeal mass that clinically looks like skin. | Pms36 | Hairy polyp |
