WSI21-141-Case-46

From MGH Learn Pathology
WSI21-141-Case-46
35M with PMH gynecomastia now with new, large aortocaval mass c/f malignancy; Retroperitoneal mass FNA.
Positive for neoplastic cells- metastatic seminoma Note: The biopsy shows sheets of discohesive, uniform appearing but degenerated tumor cells with prominent nucleoli. Immunohistochemical stains show the tumor cells to be positive for OCT3/4, b-HCG (weak, patchy) and negative for CD30 and AFP. This immunoprofile in the context of a testicular mass supports the diagnosis.
December 31, 1969 7:00:00 PM