WSI21-139: Lymph Nodes
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Toggle columns: Diagnosis
| Case | Clinical history | Requester | Diagnosis |
|---|---|---|---|
| Case | Clinical history | Requester | Diagnosis |
|
| 82F. Right neck lymphadenopathy. Level IV lymph node FNA. | Iac0 | Metastatic papillary thyroid carcinoma. |
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| 52M. Left inguinal lymph node FNA. | Iac0 | Acute neutrophilic necrotizing lymphadenitis • secondary to syphilis infection. |
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| 74 y/old M with CLL and clinical suspicion for fungemia | Lcm51 | Cryptococcus. Small mature lymphocytes • consistent with CLL. |
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| Lytic appearing osseous lesion and omental lesion (this sample) | Lcm51 | Low grade B cell lymphoma (Follicular Lymphoma) |
|
| History of testicular mass. | Iac0 | Metastatic seminoma. |
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| 69 year old M with new lymphadenopathy. | Aja51 | Mantle cell lymphoma |
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| 83 y/old F with superior mediastinum mass associated with cervical and thoracic lymphadenopathy | Aja51 | Diffuse Large B cell lymphoma • germinal center type. |
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| 77F. Cervical lymphadenopathy | Iac0 | Diffuse large B-cell lymphoma. |
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| 43yo M with supraclavicular lymphadenopathy | Mlz8 | EBV-positive DLBCL |
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| 80 y/old M with multiple enlarged LNs on the upper chest and neck. | Lcm51 | Mantle cell lymphoma (CD20/CD5 positive flow cytometry) |
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| 65 y/old M with sclerotic bone lesions • splenomegaly • IGA monoclonal spike • malaise and lymphadenopathy | Lcm51 | Diffuse Castleman's disease • plasma cell variant (patient has POEMS syndrome) |
|
| 77 YO female with an enlarged right neck lymph node | Ndk6 | B-cell lymphoma with medium-to-large cells |
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| 78 YO female with h/o grade 1 follicular lymphoma. Enlarged right inguinal lymph node. | Ndk6 | Consistent with involvement by lymphoma |
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| 78 YO female with h/o melanoma and new enlarged axillary lymph node | Ndk6 | Metastatic melanoma |
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| 70 yo F with cardiac tamponade and retroperitoneal lymphadenopathy. | Cfh13 | Atypical. Polymorphous lymphoid population including atypical large cells against a background of abundant histiocytes. Concurrent core biopsy: Consistent with peripheral T-Cell lymphoma with T-cell follicular helper phenotype. |
|
| hx of Li-Fraumeni syndrome- IDC grade 3 • poorly differentiated adrenal cortical carcinoma • leiomyosarcoma now with enlarged lymph nodes including left axillary lymph node Imaging showed a rupture left breast implant | Est105 | reactive changes consistent with a rupture implant |
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| 79 yo M with a history of DLBCL on treatment with new retroperitoneal lymphadenopathy. | Cfh13 | Positive for malignant cells. Morphologically consistent with diffuse large B-cell lymphoma. |
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| 18 yo F with abdominal pain and a new pelvic nodule. | Cfh13 | Positive for Malignant Cells. Anaplastic Large T-cell lymphoma. |
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| 60 yo F with diffuse abdominal lymphadenopathy. | Cfh13 | Diffuse large B-cell lymphoma (DLBCL) |
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| 63 yo man with a prominent neck node and no known prior malignancies | Cfh13 | Metastatic melanoma |
|
| 61 yo woman with cervical lymphadenopathy | Cfh13 | No malignant cells identified.
Polymorphous lymphocytes • consistent with reactive lymph node. Prominent lymphoglandular bodies. |
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| 74 yo F with enlarging left superior mediastinal lymph node. History of breast and uterine ca. | Ndk6 | Metastatic adenocarcinoma consistent with breast primary |
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| 29M • enlarged left axillary lymph node | Mlz8 | Classic Hodgkin lymphoma • mixed cellularity type |
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| 73M • enlarged right axillary lymph node | Mlz8 | Reactive follicular hyperplasia |
|
| 76 yo F with enlarged supraclavicular lymph node | Ndk6 | POSITIVE FOR MALIGNANT CELLS.
- Metastatic carcinoma with features suggestive of squamous cell carcinoma - Atypical lymphoid population consistent with involvement by the patient's known chronic lymphocytic leukemia. |
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| 64 yo F | Ndk6 | POSITIVE FOR MALIGNANT CELLS - Consistent with the patient's known high-grade B-cell lymphoma. |
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| 10 yo M with several months of cervical lymphadenopathy up to 3 cm. | Cfh13 | No malignant cells identified. Polymorphous lymphocytes with reactive germinal centers and prominent emperipolesis. Note: The findings are overall consistent with a reactive lymph node; however • the emperipolesis raises the possibility of Rosai-Dorfman disease. |
|
| 25 yo female | Dc679 | Hodgkin Lymphoma |
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| 90 yo male with enlarged right cervical lymph node | Ndk6 | Metastatic melanoma |
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| 76 yo f with h/o NSCLC and lymphoma with enlarging FDG avid R SCV LN | Ndk6 | Metastatic adenocarcinoma |
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| 33M • mediastinal mass. Hilar lymphadenopathy. | Iac0 | Hodgkin lymphoma. |
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| 60 year old HIV positive male with enlarged peri-pancreatic lymph node. | Mbp1 | Cryptococcal lymphadenitis |
