WSI21-133: Urine and Bladder Washings
From MGH Learn Pathology
Request details
Toggle columns: Diagnosis
Case | Clinical history | Requester | Diagnosis |
---|---|---|---|
Case | Clinical history | Requester | Diagnosis |
| 78-year-old male. Hematuria. | Iac0 | Small cell carcinoma. |
| 68-year-old male. History of diffuse large B cell lymphoma. | Iac0 | B-cell lymphoma involving urine. |
| 59-year-old male with urinary frequency; voided urine | Sj82 | Urothelial cells with degenerative changes
Crystals Starch |
| 50 year old man with hematuria and a history of renal calculi. Upper tract urine. | Cfh13 | Negative for High Grade Urothelial Carcinoma. Reactive urothelial cells. |
| 78 year old man with microscopic hematuria. | Cfh13 | High Grade Urothelial Carcinoma. |
| 79 yo man with hematuria. | Cfh13 | Negative for high grade urothelial carcinoma. Reactive urothelial and squamous cells. |
| 75 yo man with a history of urothelial carcinoma treated with BCG. | Cfh13 | Negative for high grade urothelial carcinoma.
Casts. Benign urothelial cells. Granulomas consistent with BCG treatment. |
| 66 yo woman with hematuria. | Cfh13 | Atypical.
Red blood cells. Atypical transitional cells • singly and in clusters with degenerative changes. Degenerated cells with cytopathic changes consistent with Human polyomavirus effect. |
| 73 yo man with LUTS. | Cfh13 | Suspicious for high-grade urothelial carcinoma. Rare highly-atypical transitional cells • suspicious for high-grade urothelial cell carcinoma. |
| 70 yo man with remote history of urothelial carcinoma. | Cfh13 | Suspicious for malignancy. Markedly atypical urothelial cells • suspicious for high-grade urothelial carcinoma. |
| 76 yo man with smoking history. | Cfh13 | Suspicious for malignancy. Atypical urothelial cells • some with degenerative changes. |
| 54 yo man with a space filling bladder lesion on imaging. | Cfh13 | Positive for high-grade urothelial carcinoma. |
| 70M with multiple bladder lesions | Mlz8 | Poorly differentiated carcinoma |
| 28 yo F with neurogenic lower urinary tract symptoms and peripheral eosinophilia. Prior bladder biopsy showing eosinophilic cystitis. | Cfh13 | Negative for High Grade Urothelial carcinoma. Mixed inflammation including eosinophils. |
| 73 yo man with a history of urothelial carcinoma and changes on cystoscopy consistent with inflammation. | Cfh13 | High-grade urothelial carcinoma. Polyomavirus effect. |
| 64 yo man with a history of prostate carcinoma. | Cfh13 | Positive for malignant cells. Metastatic carcinoma • consistent with the patient's prior prostate carcinoma. |
| 57 yo male with hematuria | Ndk6 | High grade urothelial cell carcinoma with squamous differentiation |
| Bladder wash from 75 yo female | Ndk6 | High grade urothelial cell carcinoma |
| 60ish year old female with prior history of tumor in bladder. | Tlh39 | Metastatic small cell neuroendocrine carcinoma. |
| 65 yo M with gross hematuria | Tz046 | Negative for HGUC. Alternaria conidia. |
| Ileal conduit • history of high-grade urothelial carcinoma. | Iac0 | Abundant degenerated cells consistent with ileal loop specimen. Guar cells from the Coloplast SenSura Mio ostomy wafer adhesive present. |
| 81M | Mlz8 | LGUN (LGUC on biopsy) |
| 86 yo male with history of bladder cancer | Ndk6 | High-grade urothelial carcinoma |
| 66 yo male with new mass noted on recent CT scan | Ndk6 | High-grade urothelial cell carcinoma |
| 84 yo f with history of bladder cancer | Ndk6 | High-grade urothelial cell carcinoma |
| 87 yo m with history of bladder cancer | Ndk6 | NEGATIVE FOR HIGH GRADE UROTHELIAL CARCINOMA Reactive urothelial cells • neutrophils • red blood cells • bacteria • and fungal organisms morphologically consistent with Candida species. |
| 86 yo M | Ndk6 | High grade urothelial cell carcinoma |
| 68 yo M w/ mass noted on recent CT scan | Ndk6 | High grade urothelial cell carcinoma |
| 51-year-old man with hematuria | Lt511 | papillary clusters of atypical urothelial cells consistent with papillary neoplasia • favor papillary urothelial carcinoma • low grade 1-2 |
| 86 yo male with hematuria | Ndk6 | Poorly differentiated carcinoma with neuroendocrine differentiation Note: Immunohistochemistry - tumor cells are focally positive for MNF116 and synaptophysin. They are negative for CD20 and CD3. |
| 84-year-old man with hematuria | Lt511 | High grade urothelial carcinoma with squamous differentiation |
| 66 yo male with hematuria | Ndk6 | High-grade urothelial cell carcinoma |
| 26 yo male with hematuria | Ndk6 | NEGATIVE FOR HIGH GRADE UROTHELIAL CARCINOMA- Neutrophilic and multinucleated giant cell reaction to Schistosomal eggs • consistent with Schistosomiasis |
| 66 yo male with hematuria | Ndk6 | High-grade urothelial cell carcinoma |
| 26 yo male with hematuria | Ndk6 | NEGATIVE FOR HIGH GRADE UROTHELIAL CARCINOMA- Neutrophilic and multinucleated giant cell reaction to Schistosomal eggs • consistent with Schistosomiasis |