GPR: 2021 - Week 04
From MGH Learn Pathology
You receive a page about a 50yo previously healthy woman sent to the ED from her PCP for anemia (Hct 20%), thrombocytopenia (20k/uL), and elevated LDH with schistocytes on peripheral smear. On examination, you notice slurred speech and word finding difficulty (new per husband), and see the pictured (palpable) rash.
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- Goel R, Ness PM, Takemoto CM, Krishnamurti L, King KE, Tobian AA. Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality. Blood. 2015;125(9):1470-1476. doi:10.1182/blood-2014-10-605493
- Bendapudi PK, Hurwitz S, Fry A, Marques MB, Waldo SW, Li A, Sun L, Upadhyay V, Hamdan A, Brunner AM, Gansner JM, Viswanathan S, Kaufman RM, Uhl L, Stowell CP, Dzik WH, Makar RS. Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: a cohort study. Lancet Haematol. 2017 Apr;4(4):e157-e164. doi: 10.1016/S2352-3026(17)30026-1. Epub 2017 Mar 2. PMID: 28259520.
- Moake JL. Thrombotic microangiopathies. N Engl J Med. 2002 Aug 22;347(8):589-600. doi: 10.1056/NEJMra020528. PMID: 12192020.
This week's Gross Pathology Roundup was presented by Sarah Mueller, MD, PhD on Mon, Jan 25, 2021.