GPR: 2020 - Week 48

From MGH Learn Pathology

Clinical history

78 year old with fungemia. A CHROMagar shows:


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Candida albicans
  • Smooth, creamy, white colonies with feet on blood agar
  • Apple green color on CHROMagar
  • Causes a wide variety of clinical diseases, including thrush, esophagitis, UTIs, and fungemia
  • Germ tube positive
  • Chlamydospores
  • Pseudohyphae and true hyphae



Candida tropicalis

  • Steel blue that diffuses into pink on CHROMagar
  • Blastoconidia at septa and between septa
  • Germ tube negative
  • Second most virulent Candida species after Candida albicans
  • Strong biofilm producer
  • Cream-colored dull colonies with slightly wrinkled edges



Candida krusei

  • Flat, dry pink on CHROMagar
  • Spread radially on SAB or blood agar
  • Off-white, dull colonies with smooth to lobed margins
  • Extremely elongated, rarely branched pseudohyphae
  • Germ tube negative
  • Opportunistic pathogen that causes multi drug resistant disease

  • Evan Mojica
  • Dr. Julian Villalba

This week's Gross Pathology Roundup was presented by Bianca Christensen MD on 2020-11-23.