GPR: 2020 - Week 40

From MGH Learn Pathology

Clinical history

66 year-old M with testis mass.


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  • 50% seen in men over 60yo, median age 67yo.
  • Bilaterality in up to 38% of cases.
  • Partial or complete replacement of testis by a firm, tan, cream-colored, often lobulated mass.
  • Focal areas of necrosis can be seen.
  • Involvement of epididymis or spermatic cord can be seen.




  • Average age 40 yo.
  • Well-circumscribed and lobulated, cream colored to tan mass.
  • Hemorrhage or necrosis can be seen.
  • Epididymis and spermatic cord involvement, and bilaterality uncommon.



Teratoma/ Teratoma-predominant MGCT

  • Seen in 3rd-4th decade.
  • Well-circumscribed, nodular, and firm mass with heterogeneous cut surface with solid and cystic areas (cysts with clear, white, flaky, gelatinous or mucoid material).
  • Mature tissue with hair, cartilage, bone, or teeth may be seen.



Embryonal carcinoma/ EC-predominant MGCT

  • Patients between 25-35 yo, average 32 yo.
  • Often poorly circumscribed, extending into rete testis and epididymis.
  • Prominent hemorrhage and necrosis.

Tumors of the Testis and Adjacent Structures, AFIP Atlas of Tumor Pathology, Ulbright and Young, 2013.

This week's Gross Pathology Roundup was presented by Baris Boyraz, MD on Mon, Sep 28, 2020.