GPR: 2019 - Week 14

• GPR Quiz
• Answer
• DDx1
• DDx2
• DDx3
• Acknowledgments

Clinical history

30 year old male with a crushed chest s/p MVA

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Fat emboli Seen after injury to bone or fibroadipose tissue Also associated with CPR, burns, soft tissue injury, osteomyelitis, Diabetes, barotrauma, surgeries of fatty tissues, septicemia, acute pancreatitis, fatty liver of alcoholism, and steroid therapy Petechial hemorrhages involving the white matter, not limited to the corpus callosum

Gliding Contusion Also associated with acceleration/deceleration injuries Linear or oval hemorrhages within the white matter of the first frontal gyri, caused by anterior-posterior ‘gliding’ movements of the brain

Diffuse axonal injury Injury associated with acceleration/deceleration Grossly may see petechial hemorrhages within corpus callosum and rostral midbrain

Diffuse Petechial Hemorrhages Due to thrombotic thrombocytopenic purpura (TTP) 70 year old patient with acute myeloid leukemia and associated TTP with thrombotic angiopathy Diffuse, scattered petechial hemorrhages involving the gray matter

• Dr. Hedley-Whyte
• Dr. Martinez-Lage
• Dr. Samore
• Dr. Ordulu

Dr. Hedley-Whyte

Dr. Martinez-Lage

Dr. Samore

Dr. Ordulu

GPR Quiz

Clinical history

30 year old male with a crushed chest s/p MVA

Registered users must be logged in to access the interactive quiz.

Answer

Fat emboli Seen after injury to bone or fibroadipose tissue Also associated with CPR, burns, soft tissue injury, osteomyelitis, Diabetes, barotrauma, surgeries of fatty tissues, septicemia, acute pancreatitis, fatty liver of alcoholism, and steroid therapy Petechial hemorrhages involving the white matter, not limited to the corpus callosum

DDx1

Gliding Contusion Also associated with acceleration/deceleration injuries Linear or oval hemorrhages within the white matter of the first frontal gyri, caused by anterior-posterior ‘gliding’ movements of the brain

DDx2

Diffuse axonal injury Injury associated with acceleration/deceleration Grossly may see petechial hemorrhages within corpus callosum and rostral midbrain

DDx3

Diffuse Petechial Hemorrhages Due to thrombotic thrombocytopenic purpura (TTP) 70 year old patient with acute myeloid leukemia and associated TTP with thrombotic angiopathy Diffuse, scattered petechial hemorrhages involving the gray matter

Acknowledgments

• Dr. Hedley-Whyte
• Dr. Martinez-Lage
• Dr. Samore
• Dr. Ordulu

Dr. Hedley-Whyte

Dr. Martinez-Lage

Dr. Samore

Dr. Ordulu

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This week's Gross Pathology Roundup was presented by [[| , ]] on Mon, Apr 01, 2019.This week's Gross Pathology Roundup was presented by [[| , ]] on Mon, Apr 01, 2019.