GPR: 2019 - Week 47

• GPR Quiz
• Answer
• DDx1
• DDx2
• DDx3
• Acknowledgments
• Reference(s)

Clinical history

38 yo G3P1011 s/p RCS at 39w1d. 3.0 cm tan-white solid-cystic nodule within the placental membranes.

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Mature Cystic Teratoma At least 2 germ cell layers: ectoderm, mesoderm, endoderm Cystic to solid (or a mix of both) Malignant transformation is possible (SCC is the most common) Rokitansky nodules: usually where bone, teeth, and hair are found Not associated with any fetal complication or anomalies

Fetus Papyraceous Vanishing twin Intrauterine death of one fetus in a multi-gestational pregnancy Resorbed into the placenta Pale yellow, flattened disk or plaque on the membranes or placental disc May see a pigmented macule (eyes) Skeletal components visible on x-ray

Chorangioma Most common placental tumor Single or multiple well-circumscribed ovoid nodules ranging in size Red-brown to tan-white Subchorionic or marginal Hamartoma-like growth of capillaries in the placenta > 1 cm can be a/w FGR/IUGR, preterm delivery, hydrops fetalis, stillbirth

Inflammatory Myofibroblastic Tumor Neoplasm of intermediate malignant potential Fleshy and circumscribed, solid or cystic nodule attached to the maternal surface Tan, white, or pink with myxoid features Whorled cut surface Thought to arise from the uterus and extend to the placenta

Dr. Drucilla Roberts

Dr. Drucilla Roberts

ExpertPath

Pathology Outlines

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This week's Gross Pathology Roundup was presented by Bianca Christensen, MD on Mon, Nov 18, 2019.