GPR: 2019 - Week 35

From MGH Learn Pathology

Clinical history

37 year-old M with splenomegaly and innumerable splenic lesions


GPR19-30 -littoral cell angioma.jpg


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GPR19-30 -littoral cell angioma.jpg

 
Littoral Cell Angioma
- Benign vascular tumor derived from littoral cells/red pulp lining cells

- Gross: Enlarged spleen with spongy appearance, almost always multiple lesions - Age and Gender: All ages, M=F

- Prognosis: Excellent, excision is curative
 

GPR19-30 -hamartoma.jpg

 

Splenic Hamartoma

- Rare benign tumor composed exclusively of red pulp

- Gross appearance: single, well-demarcated mass with red, bulging cut surfaces - Age and Gender: All ages, M=F

- Prognosis: Excellent, excision is curative
 

GPR19-30 -SANT.jpg

 

Sclerosing angiomatoid nodular transformation (SANT)

- Benign vascular lesion

- Gross appearance: Single, well-demarcated central mass with stellate necrosis - Tan-white cut surfaces with areas of entrapped red pulp - Age and Gender: Median age 50 years, M>F

- Prognosis: Excellent, excision is curative
 


Leonardo Boiocchi, MD

Daniel Shepard, MD

Diane Brackett, MD

This week's Gross Pathology Roundup was presented by Megan Johnson Fitzpatrick, MD on Mon, Aug 26, 2019.