GPR: 2019 - Week 30

From MGH Learn Pathology

Clinical history

45 year old male with 12 cm adrenal mass

GPR19-19 -Photo 1.jpg

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GPR19-19 -Photo 1.jpg

  • Well-circumscribed, unencapsulated
  • Glistening, variegated cut surface
  • Soft yellow areas (fatty component)
  • Firm red-brown areas (hematopoietic elements)
  • Hemorrhage and cystic change

GPR19-19 -Photo 2 2.jpg



  • Gray-pink cut surface
  • Hemorrhage
  • Cystic change
  • Circumferential rim of adrenal cortex

GPR19-19 -Photo 3.jpg



  • Well-circumscribed
  • Firm gray-white with bulging cut surface
  • Hemorrhage, necrosis, cystic degeneration

GPR19-19 -Photo 4.jpg



  • Well-circumscribed to ill-defined/ invasive
  • Solid and cystic
  • Tan-pink to yellow
  • Hemorrhage and necrosis

GPR19-19 -Photo 5.jpg


Adrenal Cortical Carcinoma

  • Bulky, irregularly shaped circumscribed
  • Heterogenous cut surface: red-brown to tan-yellow
  • Extensive necrosis, hemorrhage, and fibrosis

This week's Gross Pathology Roundup was presented by [[| , ]] on Mon, Jul 22, 2019.