Liver parenchyma with up to 40% macrovesicular steatosis. No areas of confluent necrosis are seen.
C. LIVER BIOPSY, RIGHT LOBE: Grade 3 steatosis without steatohepatitis, necrosis, or fibrosis (see note).
Note: Parts A, B, and C show fragments of liver parenchyma with grade 3 of 3 steatosis (ranging from approximately 70% to 80%), accentuated in the centrilobular zones. No classical hepatocyte ballooning is present. There is no evidence of steatohepatitis. No significant lobular inflammation is noted, and portal tracts show mild non-specific mononuclear inflammation. Trichrome stains on parts A, B, and C show no pathologic fibrosis on any of the liver specimens. PASD stains on parts A, B, and C show no PASD positive globules on any of the specimens. Iron stains on parts A, B, and C show focally increased iron in Kupffer cells."
Annotations and notes
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Clinical history
liver tx bx + level (slides 1-2) permanent (slides 3)
Diagnosis
FROZEN SECTION DIAGNOSIS #3; (RIGHT LOBE LIVER BIOPSY): Liver parenchyma with up to 40% macrovesicular steatosis. No areas of confluent necrosis are seen. C. LIVER BIOPSY, RIGHT LOBE: Grade 3 steatosis without steatohepatitis, necrosis, or fibrosis (see note). Note: Parts A, B, and C show fragments of liver parenchyma with grade 3 of 3 steatosis (ranging from approximately 70% to 80%), accentuated in the centrilobular zones. No classical hepatocyte ballooning is present. There is no evidence of steatohepatitis. No significant lobular inflammation is noted, and portal tracts show mild non-specific mononuclear inflammation. Trichrome stains on parts A, B, and C show no pathologic fibrosis on any of the liver specimens. PASD stains on parts A, B, and C show no PASD positive globules on any of the specimens. Iron stains on parts A, B, and C show focally increased iron in Kupffer cells."
Slides
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