ACUTE TUBULAR INJURY AND FOCAL TUBULAR NECROSIS ARTERIOSCLEROSIS
Note:
Histologic section from one slide labeled “Farizo, Rosa 3432841 LT kidney” show a wedge of frozen cortical tissue with about 71 glomeruli, of which 7 (10%) are globally sclerotic. Glomeruli are generally unremarkable and do not show endocapillary or mesangial hypercellularity. Adhesions, crescents, necrosis and intraluminal thrombi are not evident. There is no interstitial inflammation. A number of tubules show necrosis. Some show dilatation and intraluminal casts. Evaluation of fibrosis and tubular atrophy is limited by freezing artifact and tissue folds, but appears to involve ~5% of the cortex. Two of about 5 arteries show moderate intimal fibrosis. Arterioles are unremarkable. Vasculitis and thrombi are not present.
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Clinical history
donor bx
Diagnosis
KIDNEY (DONOR), WEDGE BIOPSY (UNOS ADHH396, LEFT): ACUTE TUBULAR INJURY AND FOCAL TUBULAR NECROSIS ARTERIOSCLEROSIS Note: Histologic section from one slide labeled “Farizo, Rosa 3432841 LT kidney” show a wedge of frozen cortical tissue with about 71 glomeruli, of which 7 (10%) are globally sclerotic. Glomeruli are generally unremarkable and do not show endocapillary or mesangial hypercellularity. Adhesions, crescents, necrosis and intraluminal thrombi are not evident. There is no interstitial inflammation. A number of tubules show necrosis. Some show dilatation and intraluminal casts. Evaluation of fibrosis and tubular atrophy is limited by freezing artifact and tissue folds, but appears to involve ~5% of the cortex. Two of about 5 arteries show moderate intimal fibrosis. Arterioles are unremarkable. Vasculitis and thrombi are not present.
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