DZI20-171: Vitreous

From MGH Learn Pathology

Request type Study
Subspecialty Eye
Set MEEI Eye Pathology Collection
Topic Vitreous
Presenter Stagner, Anna M.,MD


Toggle columns: Diagnosis

Case Clinical history Requester Diagnosis
Case Clinical history Requester Diagnosis

Case 1

Blind eye null Asteroid hyalosis. Note the following: 1. Full-thickness limbal scar with suture in the corneal stroma. 2. Corneal stromal downgrowth through the limbal scar and spreading into the angle and onto the iris surface. 3. On one side the angle has clear spaces at the site of a haptic from an intraocular lens prosthesis. 4. In the vitreous near the far peripheral retina (near the ora serrata) there are acellular basophilic particles that are birefringent with cross-polarized light. These are asteroid hyalosis particles. 5. The retinal ganglion cell layer is severely attenuated throughout the retina secondary to chronic glaucoma from the angle closure. 6. The retinal photoreceptors are attenuated to a variable degree throughout the retina. 7. The optic nerve has thickened pial septae and loss of the axon bundles along with cupping of the nerve head; these features indicate glaucomatous optic atrophy. KEY WORD: corneal scar angle closure glaucoma asteroid hyalosis optic atrophy pseudophakia retinal degeneration photoreceptor degeneration.