DZI20-135: NP
From MGH Learn Pathology
Request details
- Request type Study
- Subspecialty Neuropathology
- Set Frozens Study Set 2020
- Topic NP
- Presenter NS495 (user needs to log in to Learn Pathology)
Toggle columns: Diagnosis
| Case | Clinical history | Requester | Diagnosis |
|---|---|---|---|
| Case | Clinical history | Requester | Diagnosis |
|
| 49 yo F with cystic left cerebellar mass with associated densely enhancing component that appears vascular and has products of hemorrhage along its margins | null | Vascular tumor with hemorrhage and intracellular fat (Oil-Red-O) • consistent with hemangioblastoma (permanent dx: hemangioblastoma • WHO grade I of IV) |
|
| 25 yo with exophytic mass at right medulla | null | Low grade glial tumor with abundant Rosenthal material (permanent dx: pilocytic astrocytoma • WHO grade I) |
|
| 58 yo F with right frontal extra-axial mass (4.5 cm) | null | Meningioma (permanent dx: meningioma with atypical features and mildly elevated proliferation index) |
|
| 58 yo M with two peripherally enhancing cystic left frontal and parietal lesions | null | High grade glioma (permanent dx: glioblastoma) |
|
| 53 yo M with pineal cystic lesion (1.6 cm) | null | Pineal-type parenchyma with calcifications • no definitive lesion seen (permanent dx: pineal cyst) |
|
| 32 yo F with history of anaplastic astrocytoma s/p craniotomy for resection 10 years ago with chemoradiation • with imaging concerning for recurrence | null | Brain with infiltrating by cells of patient's known astrocytoma (permanent dx: recurrent/residual infiltrating astrocytoma) |
|
| 51 yo M with intradural tumor at L1-L2 | null | Schwannoma |
|
| 34 yo F with 2.7 cm enhancing intradural lesion at L2 | null | Suggestive of myxopapillary ependymoma (permanent dx: Schwannoma with abundant myxoid change) |
|
| 32 yo M with pituitary mass | null | Pituitary adenoma |
|
| 53 yo M with history of GBM s/p resection 2 years ago now with nodular enhancement on surveillance MRI | null | Brain with abundant tumor cells consistent with known glioblastoma |
|
| 72 yo M with multiply recurrent atypical meningioma (s/p multiple resections • radiation • brachytherapy • pembrolizumab • and Avastin) now with imaging concerning for progression | null | Meningothelial tumor consistent with known atypical meningioma • viable and without evidence of progression to anaplastic meningioma (permanent dx: recurrent/residual atypical meningioma) |
|
| 67 yo M with history of rectal carcinoma now with new brain mass | null | Malignant glioma with extensive necrosis (permanent dx: glioblastoma) |
|
| 90 yo M with possible recurrence of previously resected R. occipital melanoma s/p pembro and radiation | null | Reactive gliosis with abundant hemosiderin. Additional tissue requested. |
|
| 34 yo F with history of pituitary adenoma | null | Neoplasm with neuroendocrine features and marked pleomorphism • consistent with adenoma (permanent dx: corticotroph adenoma with elevated proliferation index) |
|
| 59 yo F with left acoustic tumor | null | Schwannoma with abundant xanthomatous change |
|
| 63 yo M with left occipital mass | null | High grade glioma (permanent dx: glioblastoma) |
|
| 50 yo M with history of recurrent frontotemporal anaplastic astrocytoma s/p multiple resections | null | Recurrent/residual glioma. No necrosis or microvascular proliferation seen (permanent dx: recurrent/residual high grade malignant astrocytoma) |
|
| 43 yo M with masslike lesion which appears to replace normal architecture of the majority of the cervical cord | null | Ependymoma (permanent dx: subependymoma) |
|
| 27 yo F with pituitary cysts | null | Consistent with contents of Rathke's cleft cyst (permanent dx: acellular fluid material consistent with contents of a Rathke's cyst) |
