DZI19-170-Case-1

Sequence	Case	Clinical history	Diagnosis
1	DZI19-170-Case-1 DZI19-170-Case-1	63 year old man with a history of non-small cell lung carcinoma with brain metastases treated with whole brain radiation, who presented with a new right cerebellar lesion. 63 year old man with a history of non-small cell lung carcinoma with brain metastases treated with whole brain radiation, who presented with a new right cerebellar lesion.	Cerebellar cortex and white matter. No tumor present. (An additional specimen was submitted subsequently showing metastatic adenocarcinoma) Cerebellar cortex and white matter. No tumor present. (An additional specimen was submitted subsequently showing metastatic adenocarcinoma)
2	DZI19-170-Case-2 DZI19-170-Case-2	32 year-old man who presented with pressure headaches, nausea, and occasional emesis, found to have a multicystic partially enhancing mass involving the inferior cerebellar vermis with an exophytic component extending into the fourth ventricle. 32 year-old man who presented with pressure headaches, nausea, and occasional emesis, found to have a multicystic partially enhancing mass involving the inferior cerebellar vermis with an exophytic component extending into the fourth ventricle.	Frozen diagnosis: Low-grade glial neoplasm with Rosenthal fibers, suggestive of pilocytic astrocytoma. (Final diagnosis: pilocytic astrocytoma) Frozen diagnosis: Low-grade glial neoplasm with Rosenthal fibers, suggestive of pilocytic astrocytoma. (Final diagnosis: pilocytic astrocytoma)
3	DZI19-170-Case-3 DZI19-170-Case-3	42 year old man with no significant past medical history who presented with headache and dizziness, found to have a 5 cm partially cystic and calcified posterior fossa mass with associated obstructive hydrocephalus 42 year old man with no significant past medical history who presented with headache and dizziness, found to have a 5 cm partially cystic and calcified posterior fossa mass with associated obstructive hydrocephalus	Frozen diagnosis: Choroid plexus neoplasm (Final diagnosis: atypical choroid plexus papilloma) Frozen diagnosis: Choroid plexus neoplasm (Final diagnosis: atypical choroid plexus papilloma)
4	DZI19-170-Case-4 DZI19-170-Case-4	39 year old woman with no significant past medical history who presented with 3 weeks of expressive aphasia. MRI shows a 3.4 cm rim-enhancing, FLAIR hyperintense, T1 hypointense left frontal lobe mass. 39 year old woman with no significant past medical history who presented with 3 weeks of expressive aphasia. MRI shows a 3.4 cm rim-enhancing, FLAIR hyperintense, T1 hypointense left frontal lobe mass.	Frozen diagnosis: Macrophage-rich lesion with scattered Creutzfeldt cells, suggestive of demyelinating process. (Final diagnosis: Demyelinating lesion) Frozen diagnosis: Macrophage-rich lesion with scattered Creutzfeldt cells, suggestive of demyelinating process. (Final diagnosis: Demyelinating lesion)

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