DZI19-121-Case-6

From MGH Learn Pathology
DZI19-121-Case-6
18 year old woman with headache and left hand/foot feeling "not normal"
Integrated diagnosis:

DIFFUSE GLIOMA, H3 G34 MUTANT

Histological diagnosis: Glioblastoma

WHO histological grade: IV

Molecular information: Histone H3: G34R MUTANT (sequencing) IDH: wildtype (IDH1/2 PCR sequencing) TP53: MUTANT (immunohistochemistry and sequencing) ATRX: MUTANT (immunohistochemistry and sequencing)

MGMT promoter: methylated (PCR)
December 31, 1969 7:00:00 PM







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